Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variation in Streptococcus pyogenes NAD+ glycohydrolase is associated with tissue tropism.

Journal of bacteriology - 1 Jul 2010

Riddle David J, Bessen Debra E, Caparon Michael G

Abstract excerpt

Streptococcus pyogenes is an important pathogen that causes a variety of diseases. The most common infections involve the throat (pharyngitis) or skin (impetigo); however, the factors that determine tissue tropism and severity are incompletely understood. The S. pyogenes NAD(+) glycohydrolase (SPN) is a virulence factor that has been implicated in contributing to the pathogenesis of severe infections. However,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Gene Expression Regulation, Enzymologic

Share to Haplotypes

Share to Streptococcus pyogenes

Share to Tropism

Source

Open in PubMed Open full text

Identifiers

PMID: 20494994
DOI: 10.1128/JB.00234-10
PMCID: PMC2897333

Genes

SPN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variation in Streptococcus pyogenes NAD+ glycohydrolase is associated with tissue tropism.PMID 20494994Read ↗

Consequences of the variability of the CovRS and RopB regulators among Streptococcus pyogenes causing human infections.Semantic proximity Read ↗

Interplay between human STING genotype and bacterial NADase activity regulates inter-individual disease variability.Semantic proximity Read ↗

The NAD-glycohydrolase (nga) gene of Streptococcus pyogenes.Semantic proximity Read ↗

Relationships between emm and multilocus sequence types within a global collection of Streptococcus pyogenes.Semantic proximity Read ↗

The emergence of successful <i>Streptococcus pyogenes</i> lineages through convergent pathways of capsule loss and recombination directing high toxin expressionSemantic proximity Read ↗

Contribution of Secreted NADase and Streptolysin O to the Pathogenesis of Epidemic Serotype M1 Streptococcus pyogenes Infections.Semantic proximity Read ↗

The Emergence of Successful Streptococcus pyogenes Lineages through Convergent Pathways of Capsule Loss and Recombination Directing High Toxin Expression.Semantic proximity Read ↗

Multilocus sequence typing of Streptococcus pyogenes representing most known emm types and distinctions among subpopulation genetic structures.Semantic proximity Read ↗

Natural variation of the streptococcal Group A carbohydrate biosynthesis genes impacts host-pathogen interactionSemantic proximity Read ↗

NAD-glycohydrolase production and speA and speC distribution in Group A streptococcus (GAS) isolates do not correlate with severe GAS diseases in the Australian population.Semantic proximity Read ↗

Quinolinate salvage and insights for targeting NAD biosynthesis in group A streptococci.Semantic proximity Read ↗

Close correlation of streptococcal DNase B (sdaB) alleles with emm genotypes in Streptococcus pyogenes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.