Variation in Streptococcus pyogenes NAD+ glycohydrolase is associated with tissue tropism.

doi:10.1128/JB.00234-10

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Article

Variation in Streptococcus pyogenes NAD+ glycohydrolase is associated with tissue tropism.

Journal of bacteriology - 1 Jul 2010

Riddle David J, Bessen Debra E, Caparon Michael G

Abstract excerpt

Streptococcus pyogenes is an important pathogen that causes a variety of diseases. The most common infections involve the throat (pharyngitis) or skin (impetigo); however, the factors that determine tissue tropism and severity are incompletely understood. The S. pyogenes NAD(+) glycohydrolase (SPN) is a virulence factor that has been implicated in contributing to the pathogenesis of severe infections. However,...

Topics

Alleles
Amino Acid Sequence
Base Sequence
DNA, Bacterial
Gene Expression Regulation, Bacterial
Gene Expression Regulation, Enzymologic
Genetic Variation
Haplotypes
Molecular Sequence Data
NAD+ Nucleosidase
Streptococcus pyogenes
Tropism

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Identifiers

PMID: 20494994
DOI: 10.1128/JB.00234-10
PMCID: PMC2897333

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