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Article

Consequences of the variability of the CovRS and RopB regulators among Streptococcus pyogenes causing human infections.

Scientific reports - 15 Jul 2015

Friães Ana, Pato Catarina, Melo-Cristino José, Ramirez Mario

Abstract excerpt

To evaluate the importance of covRS and ropB mutations in invasive disease caused by Group A Streptococci (GAS), we determined the sequence of the covRS and ropB genes of 191 isolates from invasive infections and pharyngitis, comprising a diverse set of emm types and multilocus sequence types. The production of SpeB and the activity of NAD glycohydrolase (NADase) and streptolysin S (SLS) were evaluated. The...

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Identifiers

PMID: 26174161
DOI: 10.1038/srep12057
PMCID: PMC4502508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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