Article
Close correlation of streptococcal DNase B (sdaB) alleles with emm genotypes in Streptococcus pyogenes.
Microbiology and immunology - 1 Jan 2005
Matsumoto Masakado, Sakae Kenji, Hashikawa Shinnosuke, Torii Keizo, Hasegawa Tadao, Horii Toshinobu, Endo Miyoko, Okuno Rumi, Murayama Shoko, Hirasawa Kyoko, Suzuki Rieko, Isobe Junko, Tanaka Daisuke, Katsukawa Chihiro, Tamaru Aki, Tomita Masaaki, Ogata Kikuyo, Ikebe Tadayoshi, Watanabe Haruo, Ohta Michio
Abstract excerpt
DNase B is a major nuclease and a possible virulence factor in Streptococcus pyogenes. The allelic diversity of streptococcal DNase B (sdaB) gene was investigated in 83 strains with 14 emm genotypes. Of the 15 alleles identified, 11 alleles carried only synonymous nucleotide substitutions. On the other hand, 4 alleles had a non-synonymous substitution other than synonymous substitutions, resulting in the...
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