Article
Relationships between emm and multilocus sequence types within a global collection of Streptococcus pyogenes.
BMC microbiology - 11 Apr 2008
Bessen Debra E, McGregor Karen F, Whatmore Adrian M
Abstract excerpt
BACKGROUND: The M type-specific surface protein antigens encoded by the 5' end of emm genes are targets of protective host immunity and attractive vaccine candidates against infection by Streptococcus pyogenes, a global human pathogen. A history of genetic change in emm was evaluated for a worldwide collection of > 500 S. pyogenes isolates that were defined for genetic background by multilocus sequence typing of...
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