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Article

Origin and quantification of circulating DNA in mice with human colorectal cancer xenografts.

Nucleic acids research - 1 Oct 2010

Thierry Alain R, Mouliere Florent, Gongora Celine, Ollier Jeremy, Robert Bruno, Ychou Marc, Del Rio Maguy, Molina Franck

Abstract excerpt

Although circulating DNA (ctDNA) could be an attractive tool for early cancer detection, diagnosis, prognosis, monitoring or prediction of response to therapies, knowledge on its origin, form and rate of release is poor and often contradictory. Here, we describe an experimental system to systematically examine these aspects. Nude mice were xenografted with human HT29 or SW620 colorectal carcinoma (CRC) cells and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20494973
DOI: 10.1093/nar/gkq421
PMCID: PMC2952865

Genes

BRAF
KRAS
PSAT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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