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Quantitation of cell-free DNA and RNA in plasma during tumor progression in rats

4 Feb 2013

Abstract excerpt

BACKGROUND: To clarify the implications of cell-free nucleic acids (cfNA) in the plasma in neoplastic disease, it is necessary to determine the kinetics of their release into the circulation. METHODS: To quantify non-tumor and tumor DNA and RNA in the plasma of tumor-bearing rats and to correlate such levels with tumor progression, we injected DHD/K12-PROb colon cancer cells subcutaneously into syngenic BD-IX...

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PMID: 23374730
DOI: 10.1186/1476-4598-12-8

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