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High Fragmentation Characterizes Tumour-Derived Circulating DNA

6 Sept 2011

Abstract excerpt

BACKGROUND: Circulating DNA (ctDNA) is acknowledged as a potential diagnostic tool for various cancers including colorectal cancer, especially when considering the detection of mutations. Certainly due to lack of normalization of the experimental conditions, previous reports present many discrepancies and contradictory data on the analysis of the concentration of total ctDNA and on the proportion of...

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PMID: 21909401
DOI: 10.1371/journal.pone.0023418

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