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Article

Methylation status of DDIT3 gene in Chronic Myeloid Leukemia

23 May 2010

Abstract excerpt

BACKGROUND: DNA-damage-inducible transcript 3 (DDIT3), a candidate tumor suppressor gene (TSG), has been found involved in the regulation of cellular growth and differentiation. The epigenetic changes of TSGs are recently recognized as an abnormal mechanism contributing to the development of chronic myeloid leukemia (CML). The aim of this study was to investigate the methylation status of DDIT3 gene in CML...

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PMID: 20492726
DOI: 10.1186/1756-9966-29-54

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