Article
Molecular signatures linked with aggressive behavior in basal cell carcinoma: a report of 6 cases.
The American Journal of dermatopathology - 1 Aug 2010
Fernandes Helen, Fernandes Neil, Bhattacharya Siddharth, Chen Wen, Seth Anjali, Hameed Meera, Mirani Neena, Lambert W Clark
Abstract excerpt
A small subset of basal cell carcinoma (BCC) characterized by rapid growth, recurrence, deep local invasiveness to dura, and/or bone is classified as extremely aggressive. Histologically, exclusive of invasive sites these tumors are similar to nonaggressive BCC. In the present study, we compare the molecular signatures of these 2 types of tumors. Twenty-one BCC specimens, 6 aggressive and 15 nonaggressive, were...
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