Article
Interaction between functional polymorphic variants in cytokine genes, established risk factors and susceptibility to basal cell carcinoma of skin.
Carcinogenesis - 1 Dec 2011
Rizzato Cosmeri, Canzian Federico, Rudnai Peter, Gurzau Eugen, Stein Angelika, Koppova Kvetoslava, Hemminki Kari, Kumar Rajiv, Campa Daniele
Abstract excerpt
Basal cell carcinoma (BCC) of the skin is the most common neoplasm among the Caucasian population of the Western world. Inflammation may result in oxidative stress and contribute to promotion and progression of tumors, including BCC. The role of cytokines, which are inflammatory modulators, in the biology of tumors has been extensively studied and it is well known that they are aberrantly produced by cancer...
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