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Article

Analysis of matrix metalloproteinase-1 gene polymorphisms and expression in benign and malignant breast tumors.

Cancer investigation - 1 Nov 2011

Zhou Jing, Brinckerhoff Constance, Lubert Susan, Yang Kui, Saini Jasmine, Hooke Jeffrey, Mural Richard, Shriver Craig, Somiari Stella

Abstract excerpt

A guanine insertion polymorphism in matrix metalloproteinase-1 promoter (MMP-1 2G) is linked to early onset and aggressiveness in cancer. We determined the role of MMP-1 2G on MMP-1 expression and breast cancer severity in patients with breast diseases. We observed no significant difference in genotype distribution among different disease groups. However, MMP-1 expression was significantly higher in atypical...

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Source

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Identifiers

PMID: 22011282
DOI: 10.3109/07357907.2011.621915
PMCID: PMC3609030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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