Article
Clinical significance of IL-2 and IL-10 gene polymorphisms and serum levels in patients with basal-cell carcinoma.
Biomarkers in medicine - 1 Jan 2016
Sobjanek Michał, Zabłotna Monika, Bień Ewa, Gleń Jolanta, Sokołowska-Wojdyło Małgorzata, Ruckemann-Dziurdzińska Katarzyna, Nowicki Roman
Abstract excerpt
MATERIALS & METHODS: Polymorphic variants of IL-2 gene (-330 T/G and +166 G/T), IL-10 gene (-1082 G/A and -819 C/T) and serum cytokines concentrations in the group of 179 patients with BCC and 173 controls were analyzed. RESULTS: The presence of the IL-2 -330 GG genotype or IL-10 -1082 GA increased the risk of BCC (OR 3.68) (OR 3.07). IL-10 -1082 AA or GA and IL-2 -330 GG genotype increased the risk of BCC (OR...
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