Article
ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation.
Science (New York, N.Y.) - 25 Jun 2010
Yvan-Charvet Laurent, Pagler Tamara, Gautier Emmanuel L, Avagyan Serine, Siry Read L, Han Seongah, Welch Carrie L, Wang Nan, Randolph Gwendalyn J, Snoeck Hans W, Tall Alan R
Abstract excerpt
Elevated leukocyte cell numbers (leukocytosis), and monocytes in particular, promote atherosclerosis; however, how they become increased is poorly understood. Mice deficient in the adenosine triphosphate-binding cassette (ABC) transporters ABCA1 and ABCG1, which promote cholesterol efflux from ma...
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