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Article

Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD.

Respiratory research - 20 May 2010

Budulac Simona E, Postma Dirkje S, Hiemstra Pieter S, Kunz Lisette I Z, Siedlinski Mateusz, Smit Henriette A, Vonk Judith M, Rutgers Bea, Timens Wim, Boezen H Marike

Abstract excerpt

BACKGROUND: Multidrug resistance-associated protein-1 (MRP1) protects against oxidative stress and toxic compounds generated by cigarette smoking, which is the main risk factor for chronic obstructive pulmonary disease (COPD). We have previously shown that single nucleotide polymorphisms (SNPs) i...

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Identifiers

PMID: 20487524
DOI: 10.1186/1465-9921-11-60
PMCID: PMC2882908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20487524-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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