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ATP-binding cassette (ABC) transporters in normal and pathological lung

20 Jun 2005

Abstract excerpt

ATP-binding cassette (ABC) transporters are a family of transmembrane proteins that can transport a wide variety of substrates across biological membranes in an energy-dependent manner. Many ABC transporters such as P-glycoprotein (P-gp), multidrug resistance-associated protein 1 (MRP1) and breast cancer resistance protein (BCRP) are highly expressed in bronchial epithelium. This review aims to give new insights...

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PMID: 15967026
DOI: 10.1186/1465-9921-6-59

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