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Article

ABCC1 polymorphisms contribute to level and decline of lung function in two population-based cohorts.

Pharmacogenetics and genomics - 1 Sept 2009

Siedlinski Mateusz, Boezen H M, Boer Jolanda M A, Smit Henriette A, Postma Dirkje S

Abstract excerpt

OBJECTIVE: The ATP-binding cassette transporter ABCC1 [i.e. multidrug resistance-associated protein 1 (MRP1)] is a membrane-bound pump excreting a variety of xenobiotics from the cell, and thus ABCC1 may play an important role in smoking-related lung function loss and development of chronic obstructive pulmonary disease (COPD). We earlier showed that bronchial epithelium of COPD patients have lower ABCC1...

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Source

Identifiers

PMID: 19687781
DOI: 10.1097/FPC.0b013e32832f5eff

Genes

ABCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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