Article
ABCC1 polymorphisms contribute to level and decline of lung function in two population-based cohorts.
Pharmacogenetics and genomics - 1 Sept 2009
Siedlinski Mateusz, Boezen H M, Boer Jolanda M A, Smit Henriette A, Postma Dirkje S
Abstract excerpt
OBJECTIVE: The ATP-binding cassette transporter ABCC1 [i.e. multidrug resistance-associated protein 1 (MRP1)] is a membrane-bound pump excreting a variety of xenobiotics from the cell, and thus ABCC1 may play an important role in smoking-related lung function loss and development of chronic obstr...
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