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Article

Phenotype-based search of natural mutations related to hereditary diseases existing in a closed colony of mice.

Experimental animals - 1 Jan 2010

Katoh Hideki, Nishikawa Tetsu, Kimura Jiro, Yamauchi Yumika, Takabayashi Shuji

Abstract excerpt

We attempted to detect natural mutations existing in the Jcl:ICR closed colony of mice which is maintained by random mating. We used ordinary genetic backcrosses to efficiently detect recessive mutations carried by individual mice in the colony. Crosses of DBA/2 females and ICR males were performed to obtain F(1) mice. Four F(1) females randomly selected from each cross were backcrossed to the male parent. More...

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Identifiers

PMID: 20484851
DOI: 10.1538/expanim.59.183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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