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Article

Early phenotypical diagnoses in Trembler-J mice model.

Journal of neuroscience methods - 30 Jun 2010

Rosso Gonzalo, Cal Karina, Canclini Lucía, Damián Juan Pablo, Ruiz Paul, Rodríguez Héctor, Sotelo José Roberto, Vazquez Cristina, Kun Alejandra

Abstract excerpt

Pmp-22 mutant mice (Trembler-J: B6.D2-Pmp22<Tr-J>/J), are used as a model to study Charcot-Marie-Tooth type 1A (CMT1A). The identification of individual genotypes is a routine in the management of the Tr(J) colony. The earliest phenotypic manifestation of the pmp-22 mutation is just about 20th postnatal days, when pups begin to tremble. In this study, a rapid and simple diagnostic method was developed by...

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PMID: 20416338
DOI: 10.1016/j.jneumeth.2010.04.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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