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Article

Identification of homozygous and heterozygous dy2J mice by PCR.

Neuromuscular disorders : NMD - 1 Jan 2000

Vilquin J T, Vignier N, Tremblay J P, Engvall E, Schwartz K, Fiszman M

Abstract excerpt

The dystrophia muscularis dy2J/dy2J mouse is an animal model for one form of human congenital muscular dystrophy. A point mutation in the gene coding for the laminin-2 alpha 2 chain leads to the expression of a truncated, partially functional protein. We developed a simple assay for the detection of the dy2J allele, which contains a new NdeI restriction site. Genomic DNA was prepared from animals of known status...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10677866
DOI: 10.1016/s0960-8966(99)00056-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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