Article
Circling mouse, a spontaneous mutant in the inner ear.
Experimental animals - 1 Apr 2002
Lee Jeong Woong, Ryoo Zae Young, Lee Eun Ju, Hong Sung Hwa, Chung Won Ho, Lee Hoon Taek, Chung Kil Saeng, Kim Tae Yoon, Oh Yang Seok, Suh Jun Gyo
Abstract excerpt
A spontaneous mutant was established in the ICR mouse strain. The affected mice became hyperactive at about 7 days of age, and then showed circling behavior. The body weight decreased significantly 2 weeks after birth, and developmental defects were revealed in the middle ear, cochlea, cochlear nerve, and semicircular canal areas. The mutation was inherited by an autosomal single recessive gene and is referred to...
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