Bradypneic, a new mutation in mice causing slow breathing, runting, and early death.

Abstract excerpt

A new recessive mutation, bradypneic (bd), causes variable weight retardation beginning as early as 3 to 5 days. Severely affected mice die within the first 2 weeks; less severely affected mice may survive to weaning or to adulthood and may be fertile. Bradypneic mice tested at 3 weeks or older breathed at half the normal rate, but breathing was deeper and O2 consumption per unit of body surface was normal. No...

Topics

• Animals
• Body Weight
• Crosses, Genetic
• Female
• Genes, Recessive
• Genetic Linkage
• Growth Disorders
• Kidney Cortex
• Lung
• Male
• Mice
• Mutation
• Respiration