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Article

Molecular signatures classify astrocytic gliomas by IDH1 mutation status.

International journal of cancer - 1 Mar 2011

Toedt Grischa, Barbus Sebastian, Wolter Marietta, Felsberg Jörg, Tews Björn, Blond Frederic, Sabel Michael C, Hofmann Stefanie, Becker Natalia, Hartmann Christian, Ohgaki Hiroko, von Deimling Andreas, Wiestler Otmar D, Hahn Meinhard, Lichter Peter, Reifenberger Guido, Radlwimmer Bernhard

Abstract excerpt

To identify novel glioma-associated pathomechanisms and molecular markers, we performed an array-based comparative genomic hybridization analysis of 131 diffuse astrocytic gliomas, including 87 primary glioblastomas (pGBIV), 13 secondary glioblastomas (sGBIV), 19 anaplastic astrocytomas (AAIII) and 12 diffuse astrocytomas (AII). All tumors were additionally screened for IDH1 and IDH2 mutations. Expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Isocitrate Dehydrogenase

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Share to Receptor, Fibroblast Growth Factor, Type 2

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Source

Identifiers

PMID: 20473936
DOI: 10.1002/ijc.25448

Genes

IDH1
FGFR2
IDH2
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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