Article
Contemporary prognostic signatures and refined risk stratification of gliomas: An analysis of 4400 tumors.
Neuro-oncology - 12 Jan 2025
Ghosh Hia S, Patel Ruchit V, Woodward Eleanor, Greenwald Noah F, Bhave Varun M, Maury Eduardo A, Cello Gregory, Hoffman Samantha E, Li Yvonne, Gupta Hersh, Youssef Gilbert, Spurr Liam F, Vogelzang Jayne, Touat Mehdi, Dubois Frank, Cherniack Andrew D, Guo Xiaopeng, Tavakol Sherwin, Cioffi Gino, Lindeman Neal I, Ligon Azra H, Chiocca E Antonio, Reardon David A, Wen Patrick Y, Meredith David M, Santagata Sandro, Barnholtz-Sloan Jill S, Ligon Keith L, Beroukhim Rameen, Bi Wenya Linda
Abstract excerpt
BACKGROUND: With the significant shift in the classification, risk stratification, and standards of care for gliomas, we sought to understand how the overall survival of patients with these tumors is impacted by molecular features, clinical metrics, and treatment received. METHODS: We assembled a cohort of patients with histopathologically diagnosed glioma from The Cancer Genome Atlas (TCGA), Project Genomics...
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