Article
From the Cover: Indispensability of the glutamate transporters GLAST and GLT1 to brain development.
Proceedings of the National Academy of Sciences of the United States of America - 8 Aug 2006
Matsugami Toshiko R, Tanemura Kentaro, Mieda Michihiro, Nakatomi Reiko, Yamada Keiko, Kondo Takashi, Ogawa Masaharu, Obata Kunihiko, Watanabe Masahiko, Hashikawa Tsutomu, Tanaka Kohichi
Abstract excerpt
Previous in vitro studies have shown that the neurotransmitter glutamate is important in brain development. Paradoxically, loss-of-function mouse models of glutamatergic signaling that are generated by genetic deletion of glutamate receptors or glutamate release show normal brain assembly. We exa...
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