Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Study of association between genetic polymorphisms of phospholipase A2 enzymes and Alzheimer's disease.

Arquivos de neuro-psiquiatria - 1 Apr 2010

Cordeiro Quirino, Noguti Ricardo, Bottino Cássio M C, Vallada Homero

Abstract excerpt

Several genes have been related to late-onset Alzheimer's disease (LOAD). Phospholipases A2 (PLA2) influence the processing and secretion of the amyloid precursor protein, which gives rise to the beta-amyloid peptide, the major component of the amyloid plaque in AD. Hence, in the present study, polymorphisms of three genes encoding PLA2 enzymes group (cytosolic PLA2: BanI cPLA2 polymorphism; calcium-independent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 1-Alkyl-2-acetylglycerophosphocholine Esterase
Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alleles

Share to Alzheimer Disease

Share to Case-Control Studies

Share to Genetic Predisposition to Disease

Share to Phospholipases A2, Calcium-Independent

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 20464283
DOI: 10.1590/s0004-282x2010000200007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Study of association between genetic polymorphisms of phospholipase A2 enzymes and Alzheimer's disease.PMID 20464283Read ↗

Genetic deficiency of plasma lipoprotein-associated phospholipase A2 (PLA2G7 V297F null mutation) and risk of Alzheimer's disease in Japan.Semantic proximity Read ↗

Association analysis of peroxisome proliferator-activated receptor gamma polymorphisms and late onset Alzheimer's disease in the Finnish population.Semantic proximity Read ↗

Association study of cathepsin D gene polymorphism in Iranian patients with sporadic late-onset Alzheimer's disease.Semantic proximity Read ↗

Association of clusterin gene polymorphisms with late-onset Alzheimer's disease.Semantic proximity Read ↗

Variation in the LRP-associated protein gene (LRPAP1) is associated with late-onset Alzheimer disease.Semantic proximity Read ↗

Allelic association analysis of phospholipase A2 genes with schizophrenia.Semantic proximity Read ↗

Association study of interferon-γ, cytosolic phospholipase A2, and cyclooxygenase-2 gene polymorphisms in Alzheimer disease.Semantic proximity Read ↗

Possible association between Cys311Ser polymorphism of paraoxonase 2 gene and late-onset Alzheimer's disease in Chinese.Semantic proximity Read ↗

C-338A polymorphism of the endothelin-converting enzyme (ECE-1) gene and the susceptibility to sporadic late-onset Alzheimer's disease and coronary artery disease.Semantic proximity Read ↗

Influence of lysosomal acid lipase polymorphisms on chromosome 10 on the risk of Alzheimer's disease and cholesterol metabolism.Semantic proximity Read ↗

Genetic association of an apolipoprotein C-I (APOC1) gene polymorphism with late-onset Alzheimer's disease.Semantic proximity Read ↗

Association of the p22phox polymorphism C242T with the risk of late-onset Alzheimer's disease in a northern Han Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.