Article
Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes.
PLoS genetics - 6 May 2010
Zhong Hua, Beaulaurier John, Lum Pek Yee, Molony Cliona, Yang Xia, Macneil Douglas J, Weingarth Drew T, Zhang Bin, Greenawalt Danielle, Dobrin Radu, Hao Ke, Woo Sangsoon, Fabre-Suver Christine, Qian Su, Tota Michael R, Keller Mark P, Kendziorski Christina M, Yandell Brian S, Castro Victor, Attie Alan D, Kaplan Lee M, Schadt Eric E
Abstract excerpt
Genome-wide association studies (GWAS) have demonstrated the ability to identify the strongest causal common variants in complex human diseases. However, to date, the massive data generated from GWAS have not been maximally explored to identify true associations that fail to meet the stringent level of association required to achieve genome-wide significance. Genetics of gene expression (GGE) studies have shown...
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