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Article

Breast cancer risks in women with a family history of breast or ovarian cancer who have tested negative for a BRCA1 or BRCA2 mutation.

British journal of cancer - 27 Jan 2009

Metcalfe K A, Finch A, Poll A, Horsman D, Kim-Sing C, Scott J, Royer R, Sun P, Narod S A

Abstract excerpt

Genetic testing for mutations in BRCA1 and BRCA2 is available in Canada for women with a significant family history of breast cancer. For the majority of tested women, a BRCA1 or BRCA2 mutation is not found, and counselling regarding breast cancer risk is based on the review of the pedigree. In this prospective study, we estimate breast cancer risks in women with a family history of breast cancer and for whom the...

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Age of Onset
Apoptosis Regulatory Proteins
BRCA1 Protein
BRCA2 Protein
False Negative Reactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Germ-Line Mutation

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Identifiers

PMID: 19088722
DOI: 10.1038/sj.bjc.6604830
PMCID: PMC2634722

Genes

BRCA1
BRCA2

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