Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BRCA1/2 and clinical outcome in a monoinstitutional cohort of women with hereditary breast cancer.

Oncology reports - 1 Jan 2014

Sambiasi Domenico, Lambo Rossana, Pilato Brunella, Tommasi Stefania, Trojano Giuseppe, Kardhashi Anila, Digennaro Maria, Trojano Vito, Simone Gianni, Paradiso Angelo

Abstract excerpt

The clinical outcome of BRCA mutation carriers and non-carriers still remains a topic of discussion. In order to interpret controversial data, in the present study, we analyzed a large consecutive monoinstitutional series of breast cancer patients and relatives with familial features carrying or not carrying BRCA mutations. The intense research in recent years regarding the clinical genetics of patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease-Free Survival
Share to Age of Onset

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA1 Protein

Share to BRCA2 Protein

Share to Breast Neoplasms

Share to Genetic Testing

Share to Survival Rate

Share to Treatment Outcome

Source

Identifiers

PMID: 24145998
DOI: 10.3892/or.2013.2802

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BRCA1/2 and clinical outcome in a monoinstitutional cohort of women with hereditary breast cancer.PMID 24145998Read ↗

Evaluation of family history in individuals with heterozygous BRCA pathogenic variants diagnosed with breast or ovarian cancer in a single center in Italy.Semantic proximity Read ↗

Breast cancer prognosis in BRCA1 and BRCA2 mutation carriers: an International Prospective Breast Cancer Family Registry population-based cohort study.Semantic proximity Read ↗

Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study.Semantic proximity Read ↗

Etiology of familial breast cancer with undetected BRCA1 and BRCA2 mutations: clinical implications.Semantic proximity Read ↗

Prospective blinded surveillance screening of Swedish women with increased hereditary risk of breast cancer.Semantic proximity Read ↗

Second primary breast cancer in BRCA1 and BRCA2 mutation carriers: 10-year cumulative incidence in the Breast Cancer Family Registry.Semantic proximity Read ↗

No evidence of excess breast cancer risk among mutation-negative women from BRCA mutation-positive families.Semantic proximity Read ↗

Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies.Semantic proximity Read ↗

Ovarian cancer patients at high risk of BRCA mutation: the constitutional genetic characterization does not change prognosis.Semantic proximity Read ↗

The clinical utility of genetic testing in breast cancer kindreds: a prospective study in families without a demonstrable BRCA mutation.Semantic proximity Read ↗

A method to assess the clinical significance of unclassified variants in the BRCA1 and BRCA2 genes based on cancer family history.Semantic proximity Read ↗

Accuracy of self-reported family history of cancer, mutation status and tumor characteristics in patients with early onset breast cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.