Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-base resolution mapping of H1-nucleosome interactions and 3D organization of the nucleosome.

Proceedings of the National Academy of Sciences of the United States of America - 25 May 2010

Syed Sajad Hussain, Goutte-Gattat Damien, Becker Nils, Meyer Sam, Shukla Manu Shubhdarshan, Hayes Jeffrey J, Everaers Ralf, Angelov Dimitar, Bednar Jan, Dimitrov Stefan

Abstract excerpt

Despite the key role of the linker histone H1 in chromatin structure and dynamics, its location and interactions with nucleosomal DNA have not been elucidated. In this work we have used a combination of electron cryomicroscopy, hydroxyl radical footprinting, and nanoscale modeling to analyze the structure of precisely positioned mono-, di-, and trinucleosomes containing physiologically assembled full-length...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Histones

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hydroxyl Radical

Share to Microscopy, Electron

Share to Models, Molecular

Share to Molecular Conformation

Share to Nucleosomes

Share to Protein Binding

Source

Open in PubMed Open full text

Identifiers

PMID: 20457934
DOI: 10.1073/pnas.1000309107
PMCID: PMC2906896

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-base resolution mapping of H1-nucleosome interactions and 3D organization of the nucleosome.PMID 20457934Read ↗

Emerging roles of linker histones in regulating chromatin structure and function.Semantic proximity Read ↗

Mapping the interaction surface of linker histone H1(0) with the nucleosome of native chromatin in vivo.Semantic proximity Read ↗

Single-Molecule Studies of the Linker Histone H1 Binding to DNA and the Nucleosome.Semantic proximity Read ↗

Cancer mutations rewire linker histone interaction network and compromise chromatosome stability.Semantic proximity Read ↗

Molecular architecture of heterochromatin at the nuclear periphery of primary human cellsSemantic proximity Read ↗

Structural determination of human nucleosomes reconstituted by the ExACT platformSemantic proximity Read ↗

Structure of Native Chromatin Fibres Revealed by Cryo-ET <i>in situ</i>Semantic proximity Read ↗

Chromatin condensing functions of the linker histone C-terminal domain are mediated by specific amino acid composition and intrinsic protein disorder.Semantic proximity Read ↗

Characterization of Medusavirus encoded histones reveals nucleosome-like structures and a unique linker histoneSemantic proximity Read ↗

Position and orientation of the globular domain of linker histone H5 on the nucleosome.Semantic proximity Read ↗

Nucleosome arrays reveal the two-start organization of the chromatin fiber.Semantic proximity Read ↗

Structure of the yeast nucleosome core particle reveals fundamental changes in internucleosome interactions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.