Article
Nucleosome arrays reveal the two-start organization of the chromatin fiber.
Science (New York, N.Y.) - 26 Nov 2004
Dorigo Benedetta, Schalch Thomas, Kulangara Alexandra, Duda Sylwia, Schroeder Rasmus R, Richmond Timothy J
Abstract excerpt
Chromatin folding determines the accessibility of DNA constituting eukaryotic genomes and consequently is profoundly important in the mechanisms of nuclear processes such as gene regulation. Nucleosome arrays compact to form a 30-nanometer chromatin fiber of hitherto disputed structure. Two competing classes of models have been proposed in which nucleosomes are either arranged linearly in a one-start higher order...
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