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Article

Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells.

Proceedings of the National Academy of Sciences of the United States of America - 25 May 2010

Eidenschenk Céline, Crozat Karine, Krebs Philippe, Arens Ramon, Popkin Daniel, Arnold Carrie N, Blasius Amanda L, Benedict Chris A, Moresco Eva Marie Y, Xia Yu, Beutler Bruce

Abstract excerpt

A previously unappreciated signal necessary for dendritic cell (DC)-mediated activation of natural killer (NK) cells during viral infection was revealed by a recessive N-ethyl-N-nitrosourea-induced mutation called warmflash (wmfl). Wmfl homozygotes displayed increased susceptibility to mouse cyto...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to fms-Like Tyrosine Kinase 3

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Source

Open in PubMed Open full text

Identifiers

PMID: 20457904
DOI: 10.1073/pnas.1005186107
PMCID: PMC2906899

Genes

TLR7
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20457904-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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