Article

Human NK cell deficiency as a result of biallelic mutations in <i>MCM10</i>

2019-11-02

Abstract excerpt

Human natural killer cell deficiency (NKD) arises from inborn errors of immunity that lead to impaired NK cell development, function or both. Through the understanding of the biological perturbations in individuals with NKD, requirements for the generation of terminally mature functional innate effector cells can be elucidated. Here we report a novel cause of NKD resulting from compound heterozygous mutations in M...

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Literature Corpus work: 7a1ade53-f342-5077-ab0d-2b63643147de
DOI: 10.1101/825554

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