Article
The POU transcription factor Drifter/Ventral veinless regulates expression of Drosophila immune defense genes.
Molecular and cellular biology - 1 Jul 2010
Junell Anna, Uvell Hanna, Davis Monica M, Edlundh-Rose Esther, Antonsson Asa, Pick Leslie, Engström Ylva
Abstract excerpt
Innate immunity operates as a first line of defense in multicellular organisms against infections caused by different classes of microorganisms. Antimicrobial peptides (AMPs) are synthesized constitutively in barrier epithelia to protect against microbial attack and are also upregulated in response to infection. Here, we implicate Drifter/Ventral veinless (Dfr/Vvl), a class III POU domain transcription factor, in...
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