Article
A novel single-stranded DNA-specific 3'-5' exonuclease, Thermus thermophilus exonuclease I, is involved in several DNA repair pathways.
Nucleic acids research - 1 Sept 2010
Shimada Atsuhiro, Masui Ryoji, Nakagawa Noriko, Takahata Yoshio, Kim Kwang, Kuramitsu Seiki, Fukui Kenji
Abstract excerpt
Single-stranded DNA (ssDNA)-specific exonucleases (ssExos) are expected to be involved in a variety of DNA repair pathways corresponding to their cleavage polarities; however, the relationship between the cleavage polarity and the respective DNA repair pathways is only partially understood. To understand the cellular function of ssExos in DNA repair better, genes encoding ssExos were disrupted in Thermus...
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