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Article

Conversion of the metal-specific activity of Escherichia coli Mn-SOD by site-directed mutagenesis of Gly165Thr.

Biochimica et biophysica acta - 1 Sept 2010

Osawa Masaki, Yamakura Fumiyuki, Mihara Masashi, Okubo Yuichiro, Yamada Kazuhiro, Hiraoka B Yukihiro

Abstract excerpt

Glycine 165, which is located near the active site metal, is mostly conserved in aligned amino acid sequences of manganese-containing superoxide dismutase (Mn-SOD) proteins, but is substituted to threonine in most iron-containing SODs (Fe-SODs). Because threonine 165 is located between Trp128 and...

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Identifiers

PMID: 20451673
DOI: 10.1016/j.bbapap.2010.04.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20451673-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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