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Recognition ofBorrelia burgdorferiby NOD2 Is Central for the Induction of an Inflammatory Reaction

4 May 2010

Abstract excerpt

Toll-like receptor 2 (TLR2) plays an important role in the recognition of Borrelia bacteria, the causative agent of Lyme disease, but the existence and importance of additional receptors in this process has been hypothesized. In the present study, we confirmed the role played by TLR2 in the recognition of Borrelia bacteria but also demonstrated a crucial role for the intracellular peptidoglycan receptor NOD2 for...

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PMID: 20441518
DOI: 10.1086/652871

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