Article
Genome-wide association studies and the problem of relatedness among advanced intercross lines and other highly recombinant populations.
Genetics - 1 Jul 2010
Cheng Riyan, Lim Jackie E, Samocha Kaitlin E, Sokoloff Greta, Abney Mark, Skol Andrew D, Palmer Abraham A
Abstract excerpt
Model organisms offer many advantages for the genetic analysis of complex traits. However, identification of specific genes is often hampered by a lack of recombination between the genomes of inbred progenitors. Recently, genome-wide association studies (GWAS) in humans have offered gene-level ma...
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