Article
[Breeding of ammonium-tolerant mutants of Actinobacillus succinogenes for succinic acid production and effect of ammonium].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 1 Feb 2010
Ye Guizi, Jiang Min, Chen Kequan, Li Jian, Xi Yonglan, Huang Xiumei, Wei Ping
Abstract excerpt
An ammonium-tolerant mutant of Actinobacillus succinogenes, YZ25, was obtained in the medium containing 61-242 mmol/L NH4+ after DES mutagenesis. Succinic acid produced by the mutant YZ25 reached 32.68 g/L when the medium contains 50 g/L glucose and 121 mmol/L ammonium, which was increased by 180.5% compared with that of the parent strain. The effects of different ammonium salts on the growth of the mutant and...
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