Article
[Breeding of Actinobacillus succiniogenes mutants with improved succinate production based on metabolic flux analysis].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 1 Sept 2008
Pan Lijun, Li Xingjiang, Jiang Shaotong, Wei Zhaojun, Chen Xiaohui, Cai Licheng, Wang Hefeng, Jiang Jijun
Abstract excerpt
It is very important to obtain high yield mutant strains on the base of metabolic flux analysis of Actinobacillus succinogenes S.JST for the industrial bioconversion of succinic acid. The metabolic pathway was analized at first and the flux of the metabolic networks was calculated by matrix. In order to decrease acetic acid flux, the strains mutated by soft X-ray of synchronous radiation were screened on the...
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