Article
Efficient imaging of amyloid deposits in Drosophila models of human amyloidoses.
Nature protocols - 1 May 2010
Berg Ina, Nilsson K Peter R, Thor Stefan, Hammarström Per
Abstract excerpt
Drosophila melanogaster is emerging as an important model system for neurodegenerative disease research. In this protocol, we describe an efficient method for imaging amyloid deposits in the Drosophila brain, by the use of a luminescent-conjugated oligothiophene (LCO), p-FTAA polymer probe. We also demonstrate the feasibility of co-staining with antibodies and compare the LCO staining with standard...
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