Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of Yin Yang 1-interacting partners at -1026C/A in the human iNOS promoter.

Archives of biochemistry and biophysics - 15 Jun 2010

Li Wei, Liu Hong, Fu Lingyu, Li Dejun, Zhao Yanyan

Abstract excerpt

Previously we demonstrated the association between human iNOS -1026C/A variant and susceptibility to hypertension, and found that -1026C/A altered the Yin Yang 1 (YY1)-binding pattern. In the current study, we verified that -1026C/A was located in a vital regulatory region of the iNOS promoter, wherein existed a DNA-binding complex composed of YY1, nuclear factor I (NFI) and activator protein-1 (AP-1). We also...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chlorocebus aethiops
Share to Hep G2 Cells
Share to Multiprotein Complexes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to NFI Transcription Factors

Share to Nitric Oxide Synthase Type II

Share to Response Elements

Share to Transcription Factor AP-1

Share to YY1 Transcription Factor

Source

Identifiers

PMID: 20430007
DOI: 10.1016/j.abb.2010.04.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of Yin Yang 1-interacting partners at -1026C/A in the human iNOS promoter.PMID 20430007Read ↗

Functional single nucleotide polymorphism-1026C/A of inducible nitric oxide synthase gene with increased YY1-binding affinity is associated with hypertension in a Chinese Han population.Semantic proximity Read ↗

Relationship between inducible NOS single-nucleotide polymorphisms and hypertension in Han Chinese.Semantic proximity Read ↗

Inducible nitric oxide synthase (iNOS) gene polymorphism and disease prevalence.Semantic proximity Read ↗

Functional Inducible Nitric Oxide Synthase Gene Variants Associate With Hypertension: A Case-Control Study in a Finnish Population-The TAMRISK Study.Semantic proximity Read ↗

Association of Single-Nucleotide Polymorphisms Rs2779249 (chr17:26128581 C>A) and Rs rs2297518 (chr17: chr17:27769571 G>A) of the NOS2 Gene with Tension-Type Headache and Arterial Hypertension Overlap Syndrome in Eastern Siberia.Semantic proximity Read ↗

Ischemic stroke susceptibility associated with ALPK1 single nucleotide polymorphisms by inhibiting URAT1 in uric acid hemostasis.Semantic proximity Read ↗

Yin-Yang 1 Activates Interleukin-4 Gene Expression in T CellsSemantic proximity Read ↗

The -318 C>G single-nucleotide polymorphism in GNAI2 gene promoter region impairs transcriptional activity through specific binding of Sp1 transcription factor and is associated with high blood pressure in Caucasians from Italy.Semantic proximity Read ↗

Association analysis between genetic variants in interleukin genes among different populations with hyperuricemia in Xinjiang Autonomous Region.Semantic proximity Read ↗

Molecular mechanism of monoamine oxidase A gene regulation under inflammation and ischemia‐like conditions: key roles of the transcription factors <scp>GATA</scp>2, Sp1 and <scp>TBP</scp>Semantic proximity Read ↗

Polymorphisms in the promoter region of iNOS predispose to rheumatoid arthritis in south Indian Tamils.Semantic proximity Read ↗

Peptide YY (PYY) Gene Polymorphisms in the 3′-Untranslated Region and Proximal Promoter Regions Regulate Cellular Gene Expression and PYY Secretion and Metabolic Syndrome Traits in VivoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.