Molecular mechanism of monoamine oxidase A gene regulation under inflammation and ischemia‐like conditions: key roles of the transcription factors <scp>GATA</scp>2, Sp1 and <scp>TBP</scp>

Abstract excerpt

Monoamine oxidase A (MAOA) plays important roles in the pathogenesis of several neurological and cardiovascular disorders. The mechanism of transcriptional regulation of MAOA under basal and pathological conditions, however, remains incompletely understood. Here, we report systematic identification and characterization of cis elements and transcription factors that govern the expression of MAOA gene. Extensive...

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