Article
Replication study for the association of 3 SNP loci identified in a genome-wide association study for diabetic nephropathy in European type 1 diabetes with diabetic nephropathy in Japanese patients with type 2 diabetes.
Clinical and experimental nephrology - 1 Dec 2013
Maeda Shiro, Imamura Minako, Kurashige Mahiro, Araki Shinichi, Suzuki Daisuke, Babazono Tetsuya, Uzu Takashi, Umezono Tomoya, Toyoda Masao, Kawai Koichi, Imanishi Masahito, Hanaoka Kazushige, Maegawa Hiroshi, Uchigata Yasuko, Hosoya Tatsuo
Abstract excerpt
BACKGROUND: A recent genome-wide association study for diabetic nephropathy in European type 1 diabetes identified 3 candidate loci for diabetic nephropathy. In this study, we examined the association of the 3 single nucleotide polymorphism (SNP) loci with susceptibility to diabetic nephropathy in Japanese subjects with type 2 diabetes. METHODS: We genotyped 3 SNPs, rs7583877 in AFF3, rs12437854 in the RGMA-MCTP2...
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