Article
Genetic variation at the SLC12A3 locus is unlikely to explain risk for advanced diabetic nephropathy in Caucasians with type 2 diabetes.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jul 2008
Ng Daniel P K, Nurbaya Siti, Choo Serena, Koh David, Chia Kee-Seng, Krolewski Andrzej S
Abstract excerpt
BACKGROUND: Large-scale genotyping efforts performed on Japanese subjects with type 2 diabetes have implicated polymorphisms in solute carrier family 12 (sodium/chloride transporters) member 3 (SLC12A3) as being associated with advanced diabetic nephropathy. However, it is not known whether these polymorphisms confer a risk for this complication in type 2 diabetic Caucasians. METHODS: A case-control study was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.