Article
Association of solute carrier family 12 (sodium/chloride) member 3 with diabetic nephropathy, identified by genome-wide analyses of single nucleotide polymorphisms.
Diabetes - 1 Nov 2003
Tanaka Nobue, Babazono Tetsuya, Saito Susumu, Sekine Akihiro, Tsunoda Tatsuhiko, Haneda Masakazu, Tanaka Yasushi, Fujioka Tomoaki, Kaku Kohei, Kawamori Ryuzou, Kikkawa Ryuichi, Iwamoto Yasuhiko, Nakamura Yusuke, Maeda Shiro
Abstract excerpt
To identify genetic elements that might confer susceptibility to diabetic nephropathy, we performed a genome-wide analysis of gene-based single nucleotide polymorphisms (SNPs) in a large cohort of Japanese patients with diabetes. In case-control association studies, patients with type 2 diabetes were divided into two groups, one having retinopathy as well as overt nephropathy and the other (the control group)...
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