Article
The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity.
Molecular biology of the cell - 1 Sept 2002
Henneberry Annette L, Wright Marcia M, McMaster Christopher R
Abstract excerpt
Phosphatidylcholine and phosphatidylethanolamine are the two main phospholipids in eukaryotic cells comprising ~50 and 25% of phospholipid mass, respectively. Phosphatidylcholine is synthesized almost exclusively through the CDP-choline pathway in essentially all mammalian cells. Phosphatidylethanolamine is synthesized through either the CDP-ethanolamine pathway or by the decarboxylation of phosphatidylserine,...
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