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Article

HLA and KIR frequencies in Sicilian Centenarians.

Rejuvenation research - 1 Jan 2000

Listì Florinda, Caruso Calogero, Colonna-Romano Giuseppina, Lio Domenico, Nuzzo Domenico, Candore Giuseppina

Abstract excerpt

Several studies suggest that human longevity appears to be linked inextricably with optimal functioning of the immune system, suggesting that specific genetic determinants may reside in loci that regulate the immune response, as human leukocyte antigen (HLA) and killer cell immunoglobulin-like receptor (KIR) genes. It has been suggested that longevity is associated with positive selection of alleles (i.e.,...

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Identifiers

PMID: 20426625
DOI: 10.1089/rej.2009.0984

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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