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Article

Investigation of KIR diversity in immunosenescence and longevity within the Irish population.

Experimental gerontology - 1 Aug 2004

Maxwell Lynn D, Ross Owen A, Curran Martin D, Rea I Maeve, Middleton Derek

Abstract excerpt

Natural killer (NK) cells play a pivotal role in the innate immune response. During the ageing process, variations occur in NK cell number and function. The cytolytic activity of NK cells is controlled by an array of activating and inhibitory cell surface receptors, including the killer cell immunoglobulin-like receptors (KIRs). In the present study, genetic diversity of the KIR loci was analysed with respect to...

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Identifiers

PMID: 15288696
DOI: 10.1016/j.exger.2004.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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