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Article

Association between the MHC class I gene HFE polymorphisms and longevity: a study in Sicilian population.

Genes and immunity - 1 Feb 2002

Lio D, Balistreri C R, Colonna-Romano G, Motta M, Franceschi C, Malaguarnera M, Candore G, Caruso C

Abstract excerpt

Classes I and II human leukocyte antigens (HLA) genes encode highly polymorphic heterodimeric glycoproteins involved in the control of immune responses. The HLA class I gene HFE seemingly no longer participates in immunity because it has lost its ability to bind peptides and it has acquired the a...

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Source

Identifiers

PMID: 11857056
DOI: 10.1038/sj.gene.6363823

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11857056-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Association between the MHC class I gene HFE polymorphisms and longevity: a study in Sicilian population.PMID 11857056Read ↗

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