Article
An historical approach to the genetic distribution of KIR and HLA ligands in Eastern Sicilians compared to modern descendants of their invaders.
Human immunology - 1 Jan 2018
Capittini Cristina, Messina Francesco, Puglisi Fabrizio, Azzaro Maria, Toscano Sebastiana, De Silvestri Annalisa, Tinelli Carmine, Sortino Grazia
Abstract excerpt
A geographical stratification of Killer Immunoglobulin-like Receptors (KIR) has been reported worldwide. We first analyzed the distribution of 15 KIR genes in a sample of 50 East-Sicilians (ES). We used a Principal Component Analysis (PCA) to compare the KIR genetic content among ES and 10 modern populations who are descendants of the ancient invaders of Sicily: Spanish, French, Norwegians, Swedes, Finns,...
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